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br Outstanding questions br Conflict of
2019-04-19
Outstanding questions Conflict of interest Acknowledgments This work was supported by the Dutch Cancer SocietyUL2015-7599 KWF (EZ). Platelets and cancer metastasis Blood platelets play a primary role in wound healing and hemostasis. Since the first observation made (on himself) by the s
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To date over mutations in KCNQ have been found to
2019-04-19
To date, over 250 mutations in KCNQ1 have been found to be linked to LQT1 [34] and new LQT1 causing mutations continue to be identified. The vast majority of KCNQ1 mutations are single nucleotide substitutions (missense) or small insertion/deletions that localize to the S1-S6 transmembrane domains [
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Education and lifestyle changes for the prevention
2019-04-19
Education and lifestyle changes for the prevention of arrhythmias are critical in BrS. Patients should be informed of the various modulators and precipitating factors that could cause malignant arrhythmias. A prominent S-wave in Lead I has recently been identified as an ECG marker of BrS [298A]. Fev
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Conversion of cholesterol to bile acids
2019-04-19
Conversion of cholesterol to bile acids is the only significant catabolic pathway for elimination of excessive cholesterol in our body. Bile acids have long been recognized as important physiological agents that facilitate nitric oxide booster of dietary fats, steroids, drugs, and lipid soluble vita
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In the past three decades
2019-04-19
In the past three decades, along with rapid economic growth in China, there has been a striking increase in alcohol consumption, greater than in most other parts of the world (). Although the purchase FMK drinking level in China used to be far lower than in many high-income and middle-income countri
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No que concerne ao territ rio partimos do princ
2019-04-18
No que concerne ao território, partimos do princípio de que os traços culturais de um grupo humano são inseparáveis de suas estruturas espaciais, sendo domoic acid apreensão do espaço crucial para que os grupos étnicos construam e comuniquem suas identidades e diferenças. Para ElHajji, o desejo de d
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br La flor de Coleridge
2019-04-18
La flor de Coleridge En el ensayo de ese nombre contenido en Otras inquisiciones leemos: De inmediato, y como corolario de estas ideas, nuestro ensayista da un salto para instalarnos en un mundo donde esta probabilidad se cumple: Como en el universo de Tlön, y siguiendo las premisas del idealis
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A year old woman was referred to our medical center
2019-04-18
A 77-year-old woman was referred to our medical center for second opinion for refractory CMML-2. She had been incidentally found to have mild leukocytosis, anemia, and thrombocytosis on routine laboratory analysis. At diagnosis her white blood cell count (WBC) was 12×10/L, hemoglobin was 10.8g/dL, a
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While it has been reported that the combination therapy of
2019-04-18
While it has been reported that the combination therapy of As2O3 and ATRA is highly effective not only as the front-line treatment [6], but also in relapsed and treatment-refractory APL patients [7], showing fewer adverse events than the combination of ATRA and chemotherapeutic drugs, the efficacy a
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Biological mechanisms have also been
2019-04-18
Biological mechanisms have also been associated with poor cardiovascular outcomes in ICD patients with depression, such as alteration of cardiac autonomic tone, activation of the sympathetic nervous system, enhanced activity of the hypothalamic-pituitary-adrenal axis, and elevated inflammatory and p
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CA-074 Several cases of injury to the circumflex artery owin
2019-04-18
Several cases of injury to the circumflex artery owing to ablation of the lateral mitral isthmus and inside the CS have been reported. The circumflex artery and the CS share a close relationship. Takahashi et al. reported the first case of acute circumflex artery occlusion during CS ablation, which
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Alvespimycin br Conclusions br Conflict of interest
2019-04-18
Conclusions Conflict of interest Introduction Case report A 26-year-old woman in the 19th week of her first pregnancy presented with a chief complaint of palpitations. Electrocardiogram (ECG) showed sustained AT with heart rate (HR) of 180bpm. The P wave morphology was positive in the in
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br Results br Discussion We identified a novel heterozygous
2019-04-18
Results Discussion We identified a novel, heterozygous nonsense SCN5A mutation, Q779X, in a family with overlapped phenotype with progressive conduction defects and BrS. The proband suffered from SSS at the age of three, and subsequent ventricular fibrillation with a coved type Brugada ECG pat
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In our study the levels of BALP PINP and CTx
2019-04-18
In our study, the levels of BALP, PINP and β-CTx in the serum were significantly (pbuy I-BET-762 markers indicate that the bone formation and bone absorption occur at the same time in patients with BM. Another feature of our research was that we used BTMs clinically to predict the risk of SREs. We
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protease inhibitor Economic sanctions have exacerbated the
2019-04-18
Economic sanctions have exacerbated the brutality of this conflict many-fold, removing any prospects for peace and reconciliation. We need some reality to gauge their manifold effects before Syria descends into another Iraq, the devastating health consequences of which were well documented. Syria u
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