• Although no GWAS results have been

  2019-05-15

  

  Although no GWAS results have been reported so far from Asian populations, the candidate gene approach identified SNPs in 4q25 and 1q21 as being associated with AF in Asian populations [19,20]. Conflicting data are reported in terms of 16q22; it is associated with AF in Chinese Han [37], but not in

• Bisphosphonates significantly reduce or prevent SREs The use

  2019-05-15

  

  Bisphosphonates significantly reduce or prevent SREs. The use of Zol for patients with bone metastases is currently the gold standard treatment [4]. However, it is still unclear whether Zol contributes to a survival benefit [9]. Niikura et al. recently reported that Zol did not prolong progression-f

• Desde mediados de la d cada

  2019-05-14

  

  Desde mediados de la década de los sesenta, la embajada argentina pedía informes sobre las actividades políticas en general y sobre las consideradas subversivas en Guatemala. A juicio de la embajada, en 1978 no se podía analizar la “ola de violencia” en Guatemala sin incluirla en el contexto de lo q

• br Drug resistant tuberculosis threatens to undermine advanc

  2019-05-14

  

  Drug-resistant tuberculosis threatens to undermine advances in tuberculosis control worldwide. Multidrug-resistant tuberculosis (MDRTB), defined as resistance to isoniazid and rifampicin, requires treatment for up to 24 months with expensive diagnostics and second-line drugs. Fewer than 15% of pat

• Hydrogen peroxide H O is shown

  2019-05-14

  

  Hydrogen peroxide (H2O2) is shown to readily promote EADs and triggered activity in isolated rat and rabbit ventricular myocytes by increasing both the L-type Ca channel (ICa-L) and late sodium currents (INa-L) [31–35]. However, this same stress fails to cause EADs in normal non-fibrotic cardiac tis

• Introduction Osteosarcoma OS is the most common primary mali

  2019-05-14

  

  Introduction Osteosarcoma (OS) is the most common primary malignant tumor of the bone. This neoplasm is defined histologically by osteoid deposition by the malignant mesenchymal meclofenamate [1]. In OS, current evidence supports an osteoblastic population as the cell of origin [2], although the di

• La cr tica realizada al ccpor las diferentes

  2019-05-14

  

  La crítica realizada al ccpor las diferentes comisiones develó la verticalidad en la toma de decisiones políticas, las cuales se agudizaban cuando se realizaban acciones militares, lo que ocasionó constantes fricciones y sanciones purchase GDC-0941 algunos miembros de la Comisión Militar o de las di

• br Introduction Despite the widespread use of bone targeted

  2019-05-13

  

  Introduction Despite the widespread use of bone-targeted agents in the care of patients with bone metastases from prostate and breast cancer, questions regarding the optimal; choice of agent, dose, dosing frequency, and duration of therapy remain unanswered [1–6]. Our research group is interested

• br Discussion The cardiac manifestations of organophosphorus

  2019-05-13

  

  Discussion The cardiac manifestations of organophosphorus poisoning are well known, involving various electrocardiographic abnormalities that may range from sinus tachycardia to ST elevation. Such most common abnormalities are sinus bradycardia, prolonged QT interval, and ST elevation [2–4]. Most

• Pilsicainide might increase hERG proteins via

  2019-05-13

  

  Pilsicainide might increase hERG proteins via facilitating the transcription of hERG from DNA to RNA or the translation of hERG RNA into hERG protein. Qualitative RT-PCR demonstrated the absence of an increase in hERG mRNA expression levels after pilsicainide treatment (Supplemental Fig. S2), indica

• No es xito peque o

  2019-05-13

  

  No es éxito pequeño que “bajo la dirección del maestro Stols” (así indica el colofón del libro) se lograse tal parecido con ellas, pero conviene subrayar que Jusep Torres Campalans no es mera mímesis material de la colección Le goût de notre temps sino también, o ante todo, estructural. El Picasso d

• In Philippe B scher and colleagues present

  2019-05-13

  

  In , Philippe Büscher and colleagues present the first formal assessment under field conditions of the HAT Sero--SeT rapid diagnostic test and compared its diagnostic accuracy with two other current serological tests: CATT and immune trypanolysis (a very sensitive and specific test that requires lab

• br The introduction of direct acting antiviral

  2019-05-13

  

  The introduction of direct-acting antiviral drugs (DAAs) is changing the treatment options for hepatitis C cannabinoid receptor (HCV). These new medicines were initially marketed at a very high price, but several countries have negotiated favourable price reductions, and, in view of the low cost

• No se trata de una simple

  2019-05-13

  

  No se trata de una simple paráfrasis de “ellos saben muy bien lo que hacen, pero aun así lo hacen”, porque al interpretar el sentido que asume el entramado social, relacional, como depositario de las “acciones” reformistas estatales, es evidente que existe una necesidad por estructurar la propia re

• A preserva o da ideia de fam lia tradicional tornou

  2019-05-13

  

  A preservação da ideia de família tradicional tornou-se uma das principais demandas desses representantes. Neste sentido, o Projeto de Lei n° 6583 de 2011, conhecido como Estatuto da Família, almeja o reconhecimento (pelo Estado) da família como uma entidade formada apenas por um homem, uma mulher e

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