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This first in human study was designed to assess the
2018-11-14
This first in human study was designed to assess the overall safety of MPC and to explore its effects on renal function in patients with moderate to severe diabetic nephropathy as assessed by glomerular filtration rate measured directly by 99Tc DTPA plasma clearance (mGFR) and estimated (eGFR) from
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br Introduction Initiating and promoting events are
2018-11-14
Introduction Initiating and promoting events are required for the development of cancer. Initiation involves genetic lesions that transform normal betaxolol cost while promoters stimulate transformed cells to proliferate and acquire more DNA changes to cause increasingly malignant behavior (Foul
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Prior to infection nasal IFN gamma levels were generally pg
2018-11-14
Prior to infection nasal IFN-gamma levels were generally epinastine hydrochloride (Lewis et al., 2012; Miller et al., 2012). However, interferon and IL-15 deficiency have been demonstrated in cultured cells retrieved from stable asthmatics at baseline following infection of these cells with a stand
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norepinephrine bitartrate br Cancer cells have altered metab
2018-11-14
Cancer norepinephrine bitartrate have altered metabolism and ongoing efforts in developing therapies that target cancer metabolism are showing promise (). However, these therapies show variable efficacy and whether the source of this variation is linked to the metabolic differences across or poss
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br Microorganism cultivation and secretome extraction The fu
2018-11-14
Microorganism cultivation and secretome extraction The fungal isolates belonging to Aspergillus sp. isolated, identified and labeled as A. fumigatus LF9 was used in this study [3]. DNA sequence of this isolate is available in GenBank under accession no. JF815073. A. fumigatus LF9 was cultivated a
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br Experimental design materials and methods br
2018-11-14
Experimental design, materials and methods Utility of language models and data Funding This work was supported by National Institutes of Health (NIH) National Library of Medicine (NLM) Grant number NIH NLM 5R01LM011176. The content is solely the responsibility of the authors and does not ne
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br Introduction The ability to anticipate where and when eve
2018-11-13
Introduction The ability to anticipate ‘where’ and ‘when’ events may occur stands as a fundamental skill which allows us to selectively orient our attention in space and time (Coull and Nobre, 1998), while ignoring a myriad of other irrelevant environmental stimuli. However, while the mechanisms
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If the amygdala cues the ventral striatum to associations be
2018-11-13
If the amygdala cues the ventral striatum to associations between valued stimuli/actions and outcomes in adult organisms in preparation for incentive-based responses, a highly reactive amygdala early in life may adaptively serve to develop this functional relationship with the ventral striatum. Whil
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This model is supported by several studies demonstrating the
2018-11-13
This model is supported by several studies demonstrating the impact of alexithymia on socio-cognitive ability, particularly in the affective domain, in both typical and atypical populations. A large body of research demonstrates that alexithymia impairs emotion recognition from both facial (Grynberg
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Las evidencias exhibidas por el
2018-11-13
Las evidencias exhibidas por el sistema holandés revelan el funcionamiento de un patrón similar. La nueva ley permite formas autorizadas de trabajo, por lo que no condona todas las instancias de prostitución. Para quienes se involucraban supuestamente de manera voluntaria en el trabajo sexual en bur
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br Acknowledgments Supported by the Russian Foundation for
2018-11-13
Acknowledgments Supported by the Russian Foundation for Basic Research (Grants 07-06-00263-а, 10-06-00114-а, and 13-06-00042-а), and by the Russian Foundation for Humanities (Grants 06-06-00375-a and 12-06-18001-e). The author is indebted to Dr Vladislav Palchikov, Dr Konstantin Danilenko, Dr Ev
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EZ Cap Reagent GG (3\' OMe) br Materials and methods br
2018-11-13
Materials and methods Results Discussion The results support our hypothesis that the pro/anti-inflammatory complement components can predict PSG sleep measures. The associations between objective sleep measures and inflammatory complement components are similar to those between objective sl
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Several geographical factors appear to have an
2018-11-13
Several geographical factors appear to have an influence on circadian preferences. For instance, a marked delay in diurnal activities was observed in local young people when moving from East to West, from South to North and from towns to villages within the same time zone in the Russian Federation [
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Several geographical factors appear to have an
2018-11-13
Several geographical factors appear to have an influence on circadian preferences. For instance, a marked delay in diurnal activities was observed in local young people when moving from East to West, from South to North and from towns to villages within the same time zone in the Russian Federation [
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We propose a simple and robust microarray
2018-11-13
We propose a simple and robust microarray immunoassay platform for simultaneous detection of two prostate cancer related biomarkers (PSA and hK2) in serum. Fig. 1 shows the layout of the platform, which simultaneously incorporates a standard curve and real sample assaying. PDMS wells in a 3×9 format
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