• The finding of an aortic phenotype in a mouse

  2018-11-09

  

  The finding of an aortic 5-aminosalicylic acid in a mouse model with a complete Smad3 deficiency very similar to the human disease supports the idea that also lack of functional SMAD3 could cause the human clinical phenotype. A similar scenario has been described for the TGF-β2 mouse model (Boileau

• In summary we performed a discovery GWAS in patients with

  2018-11-09

  

  In summary, we performed a discovery GWAS in patients with treated sepsis which focused on common genetic variants associated with 28day mortality and validated our best gene loci in independent GWA studies and an exome sequencing study. GWAS and exome data supported the VPS13A gene locus on chromos

• Compared to fMRI BOLD signals

  2018-11-09

  

  Compared to fMRI BOLD signals, which map neural activity by imaging haemodynamic responses, DC-EEG offers a more direct measure of spontaneous VLF oscillations (VLFOs), albeit with relatively limited spatial resolution. While the functional significance of VLFOs and its relation to BOLD signals cont

• Task base http www apexbt com

  2018-11-09

  

  Task-based connectivity studies of verbal WM emphasized maturational changes of within and between network functional interactions. For example, van den Bosch et al. (2014) reported age-related functional connectivity changes in children and adolescents within frontoparietal, motor and cingulate net

• Hydrogen cyanide is a potential PA biomarker If

  2018-11-09

  

  Hydrogen cyanide is a potential PA biomarker. If a point-of-care device could detect HCN in the breath of young CF patients with a pulmonary PA colonization, the need for invasive techniques and repeated anesthesia for obtaining broncho-alveolar lavage to diagnose PA would be minimized. To make a si

• Aunque la emigraci n de mexicanos hacia

  2018-11-09

  

  Aunque la emigración de mexicanos hacia aquel país es un fenómeno muy antiguo, el incremento acelerado que se ha experimentado en las últimas tres décadas no tiene punto de comparación con los antecedentes históricos del flujo migratorio entre ambos países. Como puede apreciarse en la gráfica 3, hub

• La evoluci n del balance primario

  2018-11-09

  

  La evolución del balance primario confirma este recuento. Entre 2006 y 2008 el balance primario fue positivo, pero con una tendencia descendente, methylphenidate hcl medida que los ingresos superaron a los gastos excluyendo el costo financiero de la deuda. Desde 2009, sin embargo, México ha incurrid

• La micro simulaci n de la no existencia

  2018-11-09

  

  La micro-simulación de la no existencia de transferencias por el programa Oportunidades (Cuadro 2, columnas 2ª-4ª), muestra que buy ANA 12 nivel nacional la pobreza alimentaria se hubiera incrementado a 17.72% y en el Estado de México 4.91% de los hogares estaría en este tipo de pobreza para el 2012

• Figs A to E map the spatial distribution of income

  2018-11-09

  

  Figs. 2A to 3E map the spatial distribution of income per capita and labor productivity in 1872, 1919, 1949, 1980 and 2000. Though the time benchmarks are primarily determined by the Census data, they are useful to provide a fairly broad characterization of the main phases of Brazilian development.

• br Nutrition and properties of

  2018-11-08

  

  Nutrition and properties of foods Functions of any drugs, including functional foods, are reduced with an increase in the duration of application. Repeated and long-term stimuli result in gradual carboxypeptidase or tolerance. This is a common phenomenon. However, impact of functional foods on th

• Differentiation of non selected P Olig ESCs was similar to

  2018-11-08

  

  Differentiation of non-selected P-Olig2 ESCs was similar to RW4 ESCs for all markers tested in this study. Substituting PAC for one copy of the Olig2 gene did not appear to alter differentiation of P-Olig2 ESCs into pMNs or commitment of pMNs to the MN fate. Following puromycin treatment, Olig2+ pMN

• In mice Oct encodes at least variants designated

  2018-11-08

  

  In mice, Oct4 encodes at least 2 variants, designated Oct4A and putative Oct4B. Oct4A was detected in somatic stem cells and has been recognized as a gatekeeper for maintaining pluripotency in embryonic stem cells and pre-implantation embryos. However, because of the existence of pseudogene and misi

• br Discussion We have described an approach

  2018-11-08

  

  Discussion We have described an approach that achieves inducible, retrovirus-mediated gene expression by using the coding sequence of TFs fused to an ERT2 motif. Fusion of the ERT2 motif to two TFs that regulate fate-choice decisions in the course of adult neurogenesis (i.e., ASCL1 and NEUROD1) a

• br Results br Discussion Utilizing primary breast cancer

  2018-11-08

  

  Results Discussion Utilizing primary breast cancer tissue as well as primary xenografts and established cell lines, we demonstrate that BCSCs exist in distinct mesenchymal-like and epithelial-like states that can be identified by specific marker p38 pathway and display distinct gene-expressio

• br Introduction Previously it was thought that the fully

  2018-11-08

  

  Introduction Previously, it was thought that the fully developed mammalian central nervous system (CNS) lacks significant regenerative capacity (Ramon, 1928). However, the recent discovery of neural progenitor cells, including neural stem mecamylamine (NSCs), has shown a potential for overcoming

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